Hapatra, Vizier of Poisons + Yawgmoth, Thran Physician + Obelisk Spider
Produces: Destroy all creatures opponents control, Destroy each creature that enters the battlefield under an opponent's control, Infinite -1/-1 counters, Lock, Near-infinite lifeloss, Near-infinite lifegain triggers, Near-infinite ETB, Near-infinite LTB, Near-infinite death triggers, Near-infinite sacrifice triggers, Near-infinite card draw, Near-infinite draw triggers
- Color identity
- BG
Prerequisites
You control at least one additional creature. Your life total is at least 2. An opponent controls a creature.
Steps
- Activate Yawgmoth by paying 1 life and sacrificing a creature, targeting any creature an opponent controls, putting a -1/-1 counter on a creature an opponent controls, and causing you to draw a card.
- Hapatra and Obelisk Spider's second abilities trigger.
- Resolve the Hapatra trigger, creating a 1/1 Snake creature token.
- Resolve the Obelisk Spider trigger, causing you to gain 1 life and each opponent to lose 1 life.
- Repeat.
How to execute this combo
The "Hapatra, Vizier of Poisons + Yawgmoth, Thran Physician + Obelisk Spider" combo takes 5 steps in order. Make sure you have the mana open and permanents listed in the prerequisites before you start — opponents can respond between steps.
The end result: Destroy all creatures opponents control, Destroy each creature that enters the battlefield under an opponent's control, Infinite -1/-1 counters, Lock, Near-infinite lifeloss, Near-infinite lifegain triggers, Near-infinite ETB, Near-infinite LTB, Near-infinite death triggers, Near-infinite sacrifice triggers, Near-infinite card draw, Near-infinite draw triggers.
Practice the line offline: lay out the cards, walk through each step, and note where you can lose the combo (summoning sickness, lack of priority, removal on a key permanent). In game, announce each step clearly; in casual play you can offer to shortcut after demonstrating the loop.
The best window is a turn when opponents are tapped out or after they commit a spell — hold protection (a counter, Vexing Shusher) if the combo wins on the spot.