Body of Knowledge + Niv-Mizzet, the Firemind

Prerequisites

You have a way to draw a card.

Steps

1. Draw a card.
2. Niv-Mizzet triggers, dealing 1 damage to Body of Knowledge.
3. Body of Knowledge triggers, drawing you a card.
4. Repeat.
5. Break the loop by damaging a different target with Niv-Mizzet.