Nekusar, the Mindrazer + Echo of Eons + Phyresis
Produces: Each opponent loses the game



- Color identity
- UBR
- Mana
- {4}{U}{U} if each opponent has three or more poison counters, or {6}{U}{U}{U} otherwise
Prerequisites
Phyresis attached to Nekusar.
Steps
- Cast Echo of Eons by paying {4}{U}{U}, causing each player to discard their hands and draw seven cards.
- Nekusar triggers for each card your opponents draw.
- Resolve the first trigger, causing the opponent to get a poison counter.
- If the opponent has ten or more poison counters, they lose the game as a state-based action.
- Repeat from step 3 for each remaining trigger.
- If needed, cast Echo of Eons from your graveyard for its flashback cost by paying {2}{U}, causing each player to discard their hands and draw seven cards.
- Repeat from step 2.
How to execute this combo
The "Nekusar, the Mindrazer + Echo of Eons + Phyresis" combo takes 7 steps in order. Make sure you have the mana open and permanents listed in the prerequisites before you start — opponents can respond between steps.
The end result: Each opponent loses the game.
Practice the line offline: lay out the cards, walk through each step, and note where you can lose the combo (summoning sickness, lack of priority, removal on a key permanent). In game, announce each step clearly; in casual play you can offer to shortcut after demonstrating the loop.
The best window is a turn when opponents are tapped out or after they commit a spell — hold protection (a counter, Vexing Shusher) if the combo wins on the spot.